The effects of Obesity in females and anovulatory infertility

April 7, 2018

 

One of the largest public health problems that are being identified globally at present are with women in the reproductive age.  There is an increase in these women that have anovulatory infertility.  Anovulatory infertility is when the ovaries do not release oocyte during menstruation, therefore, ovulation does not occur.

It is known from research that evidence shows that if you have a higher BMI, you are susceptible to diabetes, high blood pressure, cardiovascular disease and cancer.  Having a high BMI is also showing evidence of infertility associated with ovulatory disorders in women.  These disorders equate up to 50% of the causes of female infertility and can cause long term effects.

Women diagnosed with anovulation in their reproductive years have increased over the last 30 years with the instance of increased obesity in this age bracket.  This is showing that obese women have a higher chance of being infertile.

In the case study, women who were in excess of what is deemed as normal body weight, either much lower or much higher are in a high risk category of ovulatory infertility.  Obese women have a high instance of anovulation occurring than women with normal weight, as your weight increases so does the risk of reproductive morbidity and ovulatory disorders.

The largest endocrine organ of the body is adipose tissue, which is involved in major processes within your body, this includes reproduction. The amount of adipose tissue and where it is stored in your body has a large impact on your reproductive function.

Adipose tissue has the ability to accumulate sex hormones, which can affect the function of the reproductive axis.  Your reproductive axis relates to the hypothalamic, pituitary and gonadal axis as a single entity as they work together.  These play a critical role in the regulation of a number of different functions, including your reproductive system.

Obesity can increase your risk of irregular menstrual cycles and anovulation by signalling molecules from the adipose tissue.  With increased body mass and adipose tissue you will also see signs of increased inflammation and this will have an impact on obese women in the area of reproduction.

Menstrual dysfunction and anovulation have a much high instance in obese women and have a higher risk of poor reproductive health.

It is advised that women who are overweight pre pregnancy to consider weight loss to increase their chances of pregnancy.

 

 

 

References:

Website:         www.ncbi.nlm.mih.gov

Title:               Obesity and anovulatory infertility: A review

Link:               www.ncbi.nlm.nih.gov/pmc/articles/PMC5265624/

 

Website:         www.ncbi.nlm.mih.gov

Title:               Impact of obesity on infertility in women

Link:               www.ncbi.nlm.nih.gov/pmc/articles/PMC4456969/

 

 

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